Germline Gene Therapy

Gene Therapy is a method which employs manipulating, altering and injecting genes into a living host or cell. Starting in the 1970s, gene therapy began making the rounds in the scientific community as a new and potentially effective method of treating various genetic diseases. Some of these disorders include multiple sclerosis, sickle cell syndrome, cystic fibrosis and down syndrome. After initial research, moral debates and breakthroughs were made, the 1990s saw the age of gene therapy as a viable option. The use of stem cells and other potential religious, moral, and ethically questionable options lauded opposition from various organizations. While gene therapy research never came to a complete standstill, there were several years worth of delays and red tape. Today, laws have been passed to protect this area of research and scientists have been working diligently to make up for lost time.

One specific area of study includes germline gene therapy. Germline gene therapy works by manipulating spermatozoa and egg cells by injected genes into them. The person developed after receiving germline gene therapy would now have these altered genes intertwined into their own genetic code. This is largely thought to effect the offspring spawned from those who have received germline gene therapy, and would work to 'erase' any genetic disorders in future generations. While intial testing has been done with the use of test animals, it has never been used on human beings. Successful tests have been noted in the use of mouse eggs specifically, but its effectiveness on other animals is unknown to the public.

Germline Gene Therapy

Some fertility clinics have started to advertise a form of germline gene therapy, but for seemingly more vain reasons. These fertility clinics claim that they can predetermine the gender, height, eye color and even intelligence of a child conceived using their methods. These experimental methods cost a lot of money, so their appeal is really towards healthy, wealthy individuals with no known history of genetic disorders. Many of those against the use and development of gene therapy use examples such as these as reason enough for banning the method as a whole. Many members of the scientific community condemn these practices, but there are currently no rules in legislature preventing its usage.

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